Urocortin 2 promotes hypertrophy and enhances skeletal muscle function through cAMP and insulin/IGF-1 signaling pathways

• Main Authors: Natalia Lautherbach (Author), Dawit A.P. Gonçalves (Author), Wilian A. Silveira (Author), Sílvia Paula-Gomes (Author), Rafael Rossi Valentim (Author), Neusa M. Zanon (Author), Marcelo G. Pereira (Author), Elen H. Miyabara (Author), Luiz C.C. Navegantes (Author), Isis C. Kettelhut (Author)
• Format: Book
• Published: Elsevier, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Although it is well established that urocortin 2 (Ucn2), a peptide member of the corticotrophin releasing factor (CRF) family, and its specific corticotrophin-releasing factor 2 receptor (CRF2R) are highly expressed in skeletal muscle, the role of this peptide in the regulation of skeleta...