Early predictions of response and survival from a tumor dynamics model in patients with recurrent, metastatic head and neck squamous cell carcinoma treated with immunotherapy

• Main Authors: Ignacio González‐García (Author), Vadryn Pierre (Author), Vincent F. S. Dubois (Author), Nassim Morsli (Author), Stuart Spencer (Author), Paul G. Baverel (Author), Helen Moore (Author)
• Format: Book
• Published: Wiley, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract We developed and evaluated a method for making early predictions of best overall response (BOR) and overall survival at 6 months (OS6) in patients with cancer treated with immunotherapy. This method combines machine learning with modeling of longitudinal tumor size data. We applied our meth...