Anti-Tumor Efficiency of Perillylalcohol/β-Cyclodextrin Inclusion Complexes in a Sarcoma S180-Induced Mice Model

• Автори: Allan A. Rezende (Автор), Rafael S. Santos (Автор), Luciana N. Andrade (Автор), Ricardo G. Amaral (Автор), Matheus M. Pereira (Автор), Cristiane Bani (Автор), Mo Chen (Автор), Ronny Priefer (Автор), Classius F. da Silva (Автор), Ricardo L. C. de Albuquerque Júnior (Автор), Eliana B. Souto (Автор), Patrícia Severino (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2021-02-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

The low solubility and high volatility of perillyl alcohol (POH) compromise its bioavailability and potential use as chemotherapeutic drug. In this work, we have evaluated the anticancer activity of POH complexed with β-cyclodextrin (β-CD) using three complexation approaches. Molecular docking sugge...