Electroacupuncture reduces chronic itch via cannabinoid CB1 receptors in the ventrolateral periaqueductal gray

• Main Authors: Wen-Qiang Ge (Author), Ou-Yan (Author), Chao Chen (Author), Hong Zhang (Author), Xiao-Yu Wang (Author), Xin Liu (Author), Li Li (Author), Yu-Ye Lan (Author), Chen-Nan Li (Author), Jia-Can Sun (Author), Run-Lin Shi (Author), Zi-Yue Dou (Author), Hui-Lin Pan (Author), Hong-Ping Li (Author), Xiang-Hong Jing (Author), Man Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic itch severely reduces the quality of life of patients. Electroacupuncture (EA) is widely used to treat chronic itch. However, the underlying mechanism of this therapeutic action of EA is largely unknown. Cannabinoid CB1 receptors in the ventrolateral periaqueductal gray (vlPAG) mediate the a...