Formulation Development of Mucoadhesive Microparticle-Laden Gels for Oral Mucositis: An In Vitro and In Vivo Study

• Main Authors: Hiroomi Sakurai (Author), Yuri Ikeuchi-Takahashi (Author), Ayaka Kobayashi (Author), Nobuyoshi Yoshimura (Author), Chizuko Ishihara (Author), Tohru Aomori (Author), Hiraku Onishi (Author)
• Format: Book
• Published: MDPI AG, 2020-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In order to relieve pain due to oral mucositis, we attempted to develop mucoadhesive microparticles containing indomethacin (IM) and gel preparations with IM microparticles that can be applied to the oral cavity. The mucoadhesive microparticles were prepared with a simple composition consisting of I...