Early menopause and premature ovarian insufficiency: problems and perspectives

• Main Authors: D. V. Blinov (Author), P. L. Hasan (Author), A. N. Mnatsakanyan (Author), D. I. Korabelnikov (Author), A. T. Safarov (Author), N. V. Pavlova (Author), N. S. Zakharova (Author), D. A. Ponomarev (Author), D. A. Petrenko (Author)
• Format: Book
• Published: IRBIS LLC, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this review we summarize current data on prevalence, etiology and pathogenesis resulting in premature ovarian insufficiency (POI). In particular, genetic, autoimmune, metabolic, iatrogenic disorders as well as unfavorable impact of environmental factors represent key pathogenetic mechanisms under...