Exploring the Synergistic Effect of Bergamot Essential Oil with Spironolactone Loaded Nano-Phytosomes for Treatment of Acne Vulgaris: In Vitro Optimization, In Silico Studies, and Clinical Evaluation

• المؤلفون الرئيسيون: Rofida Albash (مؤلف), Noha M. Badawi (مؤلف), Mohammed I. A. Hamed (مؤلف), Maha H. Ragaie (مؤلف), Sahar S. Mohammed (مؤلف), Rovan M. Elbesh (مؤلف), Khaled M. Darwish (مؤلف), Manar O. Lashkar (مؤلف), Sameh S. Elhady (مؤلف), Shaimaa Mosallam (مؤلف)
• التنسيق: كتاب
• منشور في: MDPI AG, 2023-01-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

The foremost target of the current work was to formulate and optimize a novel bergamot essential oil (BEO) loaded nano-phytosomes (NPs) and then combine it with spironolactone (SP) in order to clinically compare the efficiency of both formulations against acne vulgaris. The BEO-loaded NPs formulatio...