Modular Nanotransporters Deliver Anti-Keap1 Monobody into Mouse Hepatocytes, Thereby Inhibiting Production of Reactive Oxygen Species

• Main Authors: Yuri V. Khramtsov (Author), Alexey V. Ulasov (Author), Andrey A. Rosenkranz (Author), Tatiana A. Slastnikova (Author), Tatiana N. Lupanova (Author), Georgii P. Georgiev (Author), Alexander S. Sobolev (Author)
• Format: Book
• Published: MDPI AG, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<b>Background/Objectives:</b> The study of oxidative stress in cells and ways to prevent it attract increasing attention. Antioxidant defense of cells can be activated by releasing the transcription factor Nrf2 from a complex with Keap1, its inhibitor protein. The aim of the work was to...