The regulation of plasma gelsolin by DNA methylation in ovarian cancer chemo-resistance

• Main Authors: Hafiza Bushra Manzoor (Author), Meshach Asare-Werehene (Author), Satyajit Dey Pereira (Author), Kapaettu Satyamoorthy (Author), Benjamin K. Tsang (Author)
• Format: Bog
• Udgivet: BMC, 2024-01-01T00:00:00Z.
• Fag: article
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Abstract Background Ovarian cancer (OVCA) is the most lethal gynecologic cancer and chemoresistance remains a major hurdle to successful therapy and survival of OVCA patients. Plasma gelsolin (pGSN) is highly expressed in chemoresistant OVCA compared with their chemosensitive counterparts, although...