Signaling pathways associated with interleukins 12 and 23 and epigenetic mechanism of sequential-specific regulation of expression of related genes by miRNAs as molecular markers for assessing the potential of anti-cytokine therapies

• Auteurs principaux: Beniamin O. Grabarek (Auteur), Dominika L. Wcisło-Dziadecka (Auteur), Urszula Mazurek (Auteur)
• Format: Livre
• Publié: Termedia Publishing House, 2019-03-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The molecular targeted therapy is focused on blocking the activity of specific cytokines and the signalling cascades they activate. In the treatment of psoriasis, this type of therapy is based on treatment with anti-tumor necrosis factor drugs, anti-IL-12/23, anti-IL-17, inhibitors of JAK kinases. I...