Combined Use of Cyclodextrins and Amino Acids for the Development of Cefixime Oral Solutions for Pediatric Use

• Main Authors: Marzia Cirri (Author), Natascia Mennini (Author), Giulia Nerli (Author), Jessica Rubia (Author), Enrico Casalone (Author), Fabrizio Melani (Author), Francesca Maestrelli (Author), Paola Mura (Author)
• Format: Book
• Published: MDPI AG, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cefixime (CEF) is a cephalosporin included in the WHO Model List of Essential Medicines for Children. Liquid formulations are considered the best choice for pediatric use, due to their great ease of administration and dose-adaptability. Owing to its very low aqueous solubility and poor stability, CE...