Preventive Effect of a Polyphenol-Rich Extract from <i>Geranium sanguineum</i> L. on Hepatic Drug Metabolism in Influenza Infected Mice

• Main Authors: Silviya Abarova (Author), Lyubka Tancheva (Author), Rumen Nikolov (Author), Julia Serkedjieva (Author), Elitsa Pavlova (Author), Alessia Bramanti (Author), Ferdinando Nicoletti (Author), Nikolay T. Tzvetkov (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The decreased hepatic drug metabolism (predominately first phase) is one of the essential reasons for numerous side effects and for increased drug toxicity during influenza virus infection (IVI). The present study aims to investigate some mechanisms of the preventive effect of a standardized polyphe...