A mouse model for ulcerative colitis based on NOD-scid IL2R γnull mice reconstituted with peripheral blood mononuclear cells from affected individuals

A mouse model for ulcerative colitis based on NOD-scid IL2R γnull mice reconstituted with peripheral blood mononuclear cells from affected individuals

Animal models reflective of ulcerative colitis (UC) remain a major challenge, and yet are crucial to understand mechanisms underlying the onset of disease and inflammatory characteristics of relapses and remission. Mouse models in which colitis-like symptoms are induced through challenge with toxins...

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Main Authors: Pia Palamides (Author), Henrika Jodeleit (Author), Michael Föhlinger (Author), Florian Beigel (Author), Nadja Herbach (Author), Thomas Mueller (Author), Eckhard Wolf (Author), Matthias Siebeck (Author), Roswitha Gropp (Author)
Format: Book
Published: The Company of Biologists, 2016-09-01T00:00:00Z.
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