A mouse model for ulcerative colitis based on NOD-scid IL2R γnull mice reconstituted with peripheral blood mononuclear cells from affected individuals

• 主要な著者: Pia Palamides (著者), Henrika Jodeleit (著者), Michael Föhlinger (著者), Florian Beigel (著者), Nadja Herbach (著者), Thomas Mueller (著者), Eckhard Wolf (著者), Matthias Siebeck (著者), Roswitha Gropp (著者)
• フォーマット: 図書
• 出版事項: The Company of Biologists, 2016-09-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Animal models reflective of ulcerative colitis (UC) remain a major challenge, and yet are crucial to understand mechanisms underlying the onset of disease and inflammatory characteristics of relapses and remission. Mouse models in which colitis-like symptoms are induced through challenge with toxins...