A mouse model for ulcerative colitis based on NOD-scid IL2R γnull mice reconstituted with peripheral blood mononuclear cells from affected individuals

• প্রধান লেখক: Pia Palamides (Author), Henrika Jodeleit (Author), Michael Föhlinger (Author), Florian Beigel (Author), Nadja Herbach (Author), Thomas Mueller (Author), Eckhard Wolf (Author), Matthias Siebeck (Author), Roswitha Gropp (Author)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: The Company of Biologists, 2016-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Animal models reflective of ulcerative colitis (UC) remain a major challenge, and yet are crucial to understand mechanisms underlying the onset of disease and inflammatory characteristics of relapses and remission. Mouse models in which colitis-like symptoms are induced through challenge with toxins...