In Vitro and In Vivo Antiviral Studies of New Heteroannulated 1,2,3-Triazole Glycosides Targeting the Neuraminidase of Influenza A Viruses

• Main Authors: Omnia Kutkat (Author), Ahmed Kandeil (Author), Yassmin Moatasim (Author), Yaseen A. M. M. Elshaier (Author), Wael A. El-Sayed (Author), Samir T. Gaballah (Author), Ahmed El Taweel (Author), Mina Nabil Kamel (Author), Mohamed El Sayes (Author), Mohammed A. Ramadan (Author), Rabeh El-Shesheny (Author), Farouk M. E. Abdel-Megeid (Author), Richard Webby (Author), Ghazi Kayali (Author), Mohamed A. Ali (Author)
• Format: Book
• Published: MDPI AG, 2022-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

There is an urgent need to develop and synthesize new anti-influenza drugs with activity against different strains, resistance to mutations, and suitability for various populations. Herein, we tested in vitro and in vivo the antiviral activity of new 1,2,3-triazole glycosides incorporating benzimida...