In Vitro and In Vivo Antiviral Studies of New Heteroannulated 1,2,3-Triazole Glycosides Targeting the Neuraminidase of Influenza A Viruses

• Glavni autori: Omnia Kutkat (Autor), Ahmed Kandeil (Autor), Yassmin Moatasim (Autor), Yaseen A. M. M. Elshaier (Autor), Wael A. El-Sayed (Autor), Samir T. Gaballah (Autor), Ahmed El Taweel (Autor), Mina Nabil Kamel (Autor), Mohamed El Sayes (Autor), Mohammed A. Ramadan (Autor), Rabeh El-Shesheny (Autor), Farouk M. E. Abdel-Megeid (Autor), Richard Webby (Autor), Ghazi Kayali (Autor), Mohamed A. Ali (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2022-03-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

There is an urgent need to develop and synthesize new anti-influenza drugs with activity against different strains, resistance to mutations, and suitability for various populations. Herein, we tested in vitro and in vivo the antiviral activity of new 1,2,3-triazole glycosides incorporating benzimida...