Congenital diaphragmatic hernias: from genes to mechanisms to therapies

• Main Authors: Gabrielle Kardon (Author), Kate G. Ackerman (Author), David J. McCulley (Author), Yufeng Shen (Author), Julia Wynn (Author), Linshan Shang (Author), Eric Bogenschutz (Author), Xin Sun (Author), Wendy K. Chung (Author)
• Format: Book
• Published: The Company of Biologists, 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Congenital diaphragmatic hernias (CDHs) and structural anomalies of the diaphragm are a common class of congenital birth defects that are associated with significant morbidity and mortality due to associated pulmonary hypoplasia, pulmonary hypertension and heart failure. In ∼30% of CDH patients, gen...