Preadipocytes in human granulation tissue: role in wound healing and response to macrophage polarization

• Main Authors: Tina Rauchenwald (Author), Florian Handle (Author), Catherine E. Connolly (Author), Antonia Degen (Author), Christof Seifarth (Author), Martin Hermann (Author), Christoph H. Tripp (Author), Doris Wilflingseder (Author), Susanne Lobenwein (Author), Dragana Savic (Author), Leo Pölzl (Author), Evi M. Morandi (Author), Dolores Wolfram (Author), Ira-Ida Skvortsova (Author), Patrizia Stoitzner (Author), Johannes Haybaeck (Author), Marko Konschake (Author), Gerhard Pierer (Author), Christian Ploner (Author)
• Format: Book
• Published: BMC, 2023-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Chronic non-healing wounds pose a global health challenge. Under optimized conditions, skin wounds heal by the formation of scar tissue. However, deregulated cell activation leads to persistent inflammation and the formation of granulation tissue, a type of premature scar tissue...