rPbPga1 from Paracoccidioides brasiliensis Activates Mast Cells and Macrophages via NFkB.

• Main Authors: Clarissa Xavier Resende Valim (Author), Elaine Zayas Marcelino da Silva (Author), Mariana Aprigio Assis (Author), Fabricio Freitas Fernandes (Author), Paulo Sergio Rodrigues Coelho (Author), Constance Oliver (Author), Maria Célia Jamur (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:The fungus Paracoccidioides brasiliensis is the leading etiological agent of paracoccidioidomycosis (PCM), a systemic granulomatous disease that typically affects the lungs. Cell wall components of P. brasiliensis interact with host cells and influence the pathogenesis of PCM. In yeast, m...