Condensation properties of stress granules and processing bodies are compromised in myotonic dystrophy type 1

• Asıl Yazarlar: Selma Gulyurtlu (Yazar), Monika S. Magon (Yazar), Patrick Guest (Yazar), Panagiotis P. Papavasiliou (Yazar), Kim D. Morrison (Yazar), Alan R. Prescott (Yazar), Judith E. Sleeman (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: The Company of Biologists, 2022-07-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

RNA regulation in mammalian cells requires complex physical compartmentalisation, using structures thought to be formed by liquid-liquid phase separation. Disruption of these structures is implicated in numerous degenerative diseases. Myotonic dystrophy type 1 (DM1) is a multi-systemic trinucleotide...