Inhibition of COX-2 signaling favors E. coli during urinary tract infection

• Main Authors: Soumitra Mohanty (Author), Ciska Lindelauf (Author), John Kerr White (Author), Andrea Scheffschick (Author), Ewa Ehrenborg (Author), Isak Demirel (Author), Hanna Brauner (Author), Annelie Brauner (Author)
• Format: Book
• Published: BMC, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background To avoid the overuse of antibiotics, non-steroidal anti-inflammatory drugs (NSAIDs), acting via cyclooxygenase (COX) inhibition, have been used to reduce pain and as an alternative treatment for uncomplicated urinary tract infections (UTIs). However, clinical studies evaluating N...