HBV genome-enriched single cell sequencing revealed heterogeneity in HBV-driven hepatocellular carcinoma (HCC)

• Main Authors: Wenhui Wang (Author), Yan Chen (Author), Liang Wu (Author), Yi Zhang (Author), Seungyeul Yoo (Author), Quan Chen (Author), Shiping Liu (Author), Yong Hou (Author), Xiao-ping Chen (Author), Qian Chen (Author), Jun Zhu (Author)
• Format: Book
• Published: BMC, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Hepatitis B virus (HBV) related hepatocellular carcinoma (HCC) is heterogeneous and frequently contains multifocal tumors, but how the multifocal tumors relate to each other in terms of HBV integration and other genomic patterns is not clear. Methods To interrogate heterogeneity...