Epigenetic loci for blood pressure are associated with hypertensive target organ damage in older African Americans from the genetic epidemiology network of Arteriopathy (GENOA) study

• Main Authors: Minjung Kho (Author), Wei Zhao (Author), Scott M. Ratliff (Author), Farah Ammous (Author), Thomas H. Mosley (Author), Lulu Shang (Author), Sharon L. R. Kardia (Author), Xiang Zhou (Author), Jennifer A. Smith (Author)
• Format: Book
• Published: BMC, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Hypertension is a major modifiable risk factor for arteriosclerosis that can lead to target organ damage (TOD) of heart, kidneys, and peripheral arteries. A recent epigenome-wide association study for blood pressure (BP) identified 13 CpG sites, but it is not known whether DNA me...