Preventive treatment with ginsenoside Rb1 ameliorates monocrotaline-induced pulmonary arterial hypertension in rats and involves store-operated calcium entry inhibition

• Main Authors: Rui-Xing Wang (Author), Rui-Lan He (Author), Hai-Xia Jiao (Author), Run-Tian Zhang (Author), Jing-Yi Guo (Author), Xiao-Ru Liu (Author), Long-Xin Gui (Author), Mo-Jun Lin (Author), Zhi-Juan Wu (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context Ginsenoside Rb1, the main active ingredient of ginseng, exhibits ex vivo depression of store-operated calcium entry (SOCE) and related vasoconstriction in pulmonary arteries derived from pulmonary hypertension (PH) rats. However, the in vivo effects of ginsenoside Rb1 on PH remain unclear. O...