Simultaneous Improvement of Dissolution Behavior and Oral Bioavailability of Antifungal Miconazole via Cocrystal and Salt Formation

Miconazole shows low oral bioavailability in humans due to poor aqueous solubility, although it has demonstrated various pharmacological activities such as antifungal, anti-tubercular and anti-tumor effects. Cocrystal/salt formation is one of the effective methods for solving this problem. In this s...

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Main Authors: Ksenia V. Drozd (Author), Alex N. Manin (Author), Denis E. Boycov (Author), German L. Perlovich (Author)
Format: Book
Published: MDPI AG, 2022-05-01T00:00:00Z.
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3rd Floor Main Library

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