Safety, tolerability, and pharmacokinetics of fluoropezil (DC20), a novel acetylcholinesterase inhibitor: A phase I study in healthy young and elderly Chinese subjects

• Main Authors: Hongjie Qian (Author), Chengyin Yu (Author), Huijuan Zhu (Author), Qichen Ding (Author), Yuting Cai (Author), Jiao Jing (Author), Xin Xu (Author), Runcong Guo (Author), Haiyan Zhang (Author), Hong Liu (Author), Xiaoyan Chen (Author), Yun Liu (Author)
• Format: Book
• Published: Wiley, 2023-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The present study evaluated the safety, tolerability, and pharmacokinetics of fluoropezil (DC20), a novel acetylcholinesterase inhibitor under development for the treatment of Alzheimer's disease (AD) in otherwise healthy young and elderly Chinese subjects. The study of young subjects...