Decoding the diversity of killer immunoglobulin-like receptors by deep sequencing and a high-resolution imputation method

• Autores principales: Saori Sakaue (Autor), Kazuyoshi Hosomichi (Autor), Jun Hirata (Autor), Hirofumi Nakaoka (Autor), Keiko Yamazaki (Autor), Makoto Yawata (Autor), Nobuyo Yawata (Autor), Tatsuhiko Naito (Autor), Junji Umeno (Autor), Takaaki Kawaguchi (Autor), Toshiyuki Matsui (Autor), Satoshi Motoya (Autor), Yasuo Suzuki (Autor), Hidetoshi Inoko (Autor), Atsushi Tajima (Autor), Takayuki Morisaki (Autor), Koichi Matsuda (Autor), Yoichiro Kamatani (Autor), Kazuhiko Yamamoto (Autor), Ituro Inoue (Autor), Yukinori Okada (Autor)
• Formato: Libro
• Publicado: Elsevier, 2022-03-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Summary: The killer cell immunoglobulin-like receptor (KIR) recognizes human leukocyte antigen (HLA) class I molecules and modulates the function of natural killer cells. Despite its role in immunity, the complex genomic structure has limited a deep understanding of the KIR genomic landscape. Here w...