Inhibition of intracellular proton-sensitive Ca2+-permeable TRPV3 channels protects against ischemic brain injury

Ischemic brain stroke is pathologically characterized by tissue acidosis, sustained calcium entry and progressive cell death. Previous studies focusing on antagonizing N-methyl-d-aspartate (NMDA) receptors have failed to translate any clinical benefits, suggesting a non-NMDA mechanism involved in th...

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Main Authors: Xiaoling Chen (Author), Jingliang Zhang (Author), KeWei Wang (Author)
Format: Book
Published: Elsevier, 2022-05-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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