Tiling resolution array CGH and high density expression profiling of urothelial carcinomas delineate genomic amplicons and candidate target genes specific for advanced tumors

• Main Authors: Heidenblad Markus (Author), Lindgren David (Author), Jonson Tord (Author), Liedberg Fredrik (Author), Veerla Srinivas (Author), Chebil Gunilla (Author), Gudjonsson Sigurdur (Author), Borg Åke (Author), Månsson Wiking (Author), Höglund Mattias (Author)
• Format: Bog
• Udgivet: BMC, 2008-01-01T00:00:00Z.
• Fag: article
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<p>Abstract</p> <p>Background</p> <p>Urothelial carcinoma (UC) is characterized by nonrandom chromosomal aberrations, varying from one or a few changes in early-stage and low-grade tumors, to highly rearranged karyotypes in muscle-invasive lesions. Recent array-CGH anal...