Dapagliflozin Attenuates Myocardial Fibrosis by Inhibiting the TGF-β1/Smad Signaling Pathway in a Normoglycemic Rabbit Model of Chronic Heart Failure

• Hoofdauteurs: Xuefeng Chen (Auteur), Qian Yang (Auteur), Wenlou Bai (Auteur), Wenjing Yao (Auteur), Litian Liu (Auteur), Yuanyuan Xing (Auteur), Cunliang Meng (Auteur), Peng Qi (Auteur), Yi Dang (Auteur), Xiaoyong Qi (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2022-05-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Recent studies have shown that sodium-glucose cotransporter-2 (SGLT2) inhibitors play a beneficial role for normoglycemic patients with heart failure (HF). However, the underlying mechanism remains largely unexplored. In the present study, we aimed to investigate the cardioprotective effect of SGLT2...