Omega-3 Supplementation Prevents Short-Term High-Fat Diet Effects on the α7 Nicotinic Cholinergic Receptor Expression and Inflammatory Response

• Main Authors: I. C. A. Martins (Author), L. S. Contieri (Author), C. L. Amaral (Author), S. O. Costa (Author), A. C. P. Souza (Author), L. M. Ignacio-Souza (Author), M. Milanski (Author), A. S. Torsoni (Author), M. A. Torsoni (Author)
• Format: Book
• Published: Hindawi Limited, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The study is aimed at investigating if PUFA supplementation could prevent the effects of a short-term HFD on α7nAChR expression and on the severity of sepsis. Swiss mice were used for the in vivo experiments. For the in vitro experiments, we used a microglia cell line (BV-2) and a hepatoma cell line...