Olmesartan alleviates SARS-CoV-2 envelope protein induced renal fibrosis by regulating HMGB1 release and autophagic degradation of TGF-β1

• Główni autorzy: Shilin Zhou (Autor), Zanzhe Yu (Autor), Zihui Chen (Autor), Fengling Ning (Autor), Xuetao Hu (Autor), Tiangang Wu (Autor), Mingxue Li (Autor), Hong Xin (Autor), Svetlana Reilly (Autor), Xuemei Zhang (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Background and aims: Renal damage in severe coronavirus disease 2019 (COVID-19) is highly associated with mortality. Finding relevant therapeutic candidates that can alleviate it is crucial. Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin-receptor blockers (ARBs) have been shown to...