Exploring the potential use of melatonin as a modulator of tramadol-induced rewarding effects in rats

• मुख्य लेखकों: Alqassem Y. Hakami (लेखक), Badrah S. Alghamdi (लेखक), Fahad S. Alshehri (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2024-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background:Melatonin is responsible for regulating the sleep-wake cycle and circadian rhythms in mammals. Tramadol, a synthetic opioid analgesic, is used to manage moderate to severe pain but has a high potential for abuse and dependence. Studies have shown that melatonin could be a potential modula...