Effects of genotype and food on naltrexone exposure in adolescents

• Main Authors: Stephani L. Stancil (Author), Michaela Voss (Author), Whitney Nolte (Author), John Tumberger (Author), William Adelman (Author), Susan Abdel‐Rahman (Author)
• Format: Book
• Published: Wiley, 2022-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Naltrexone (NTX), an opioid antagonist metabolized by aldo‐keto reductase 1C4 (AKR1C4), is prescribed for psychiatric conditions like eating disorders with variable response. Systemic exposure is highly variable in adults, yet no data exist in children. The purpose of this study was to eval...