Wogonin Prevents Glucocorticoid-Induced Thymocyte Apoptosis Without Diminishing Its Anti-inflammatory Action

• Main Authors: Riyo Enomoto (Author), Chiyoko Sugahara (Author), Chie Suzuki (Author), Ikumi Nagase (Author), Yoshimi Takamura (Author), Asa Yoshikawa (Author), Akiko Hosoda (Author), Hiroyuki Hirano (Author), Toshio Yokoi (Author), Eibai Lee (Author)
• Format: Book
• Published: Elsevier, 2007-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The effect of wogonin, a flavone highly purified from the roots of Scutellaria baicalensis, on apoptotic cell death was re-evaluated in rat thymocytes. This flavone inhibited glucocorticoid-induced apoptotic changes such as DNA fragmentation, phosphatidylserine translocation, and nuclear condensatio...