Assessing biological and technological variability in protein levels measured in pre-diagnostic plasma samples of women with breast cancer

• Main Authors: Christine Y. Yeh (Author), Ravali Adusumilli (Author), Majlinda Kullolli (Author), Parag Mallick (Author), Esther M. John (Author), Sharon J. Pitteri (Author)
• Format: Book
• Published: BMC, 2017-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Quantitative proteomics allows for the discovery and functional investigation of blood-based pre-diagnostic biomarkers for early cancer detection. However, a major limitation of proteomic investigations in biomarker studies remains the biological and technical variability in the...