Pharmacokinetics of fluorobenzyl polyethylene glycol conjugated tetraiodothyroacetic acid (NP751), a novel anticancer thyrointegrin αvβ3 antagonist

We have recently reported on the development of fb-PMT (NP751), a conjugate of the thyroid hormone metabolite tetraiodothyroacetic acid (tetrac) and monodisperse polyethylene glycol 36. It exhibited high affinity for thyrointegrin αvβ3 receptor and potent anti-angiogenic and anticancer activity in v...

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Main Authors: Kazutoshi Fujioka (Author), Bruce A. Hay (Author), Kavitha Godugu (Author), Shaker A. Mousa (Author)
Format: Book
Published: Frontiers Media S.A., 2022-11-01T00:00:00Z.
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