Indoxyl-Sulfate-Induced Redox Imbalance in Chronic Kidney Disease

• Egile Nagusiak: Chien-Lin Lu (Egilea), Cai-Mei Zheng (Egilea), Kuo-Cheng Lu (Egilea), Min-Tser Liao (Egilea), Kun-Lin Wu (Egilea), Ming-Chieh Ma (Egilea)
• Formatua: Liburua
• Argitaratua: MDPI AG, 2021-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

The accumulation of the uremic toxin indoxyl sulfate (IS) induces target organ damage in chronic kidney disease (CKD) patients, and causes complications including cardiovascular diseases, renal osteodystrophy, muscle wasting, and anemia. IS stimulates reactive oxygen species (ROS) production in CKD,...