Physcion inhibition of CYP2C9, 2D6 and 3A4 in human liver microsomes

• Autori principali: Lu Liu (Autore), Sen Sun (Autore), Xiaohua Li (Autore)
• Natura: Libro
• Pubblicazione: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

AbstractContext The effect of the active ingredients in traditional Chinese medicines on the activity of cytochrome P450 enzymes (CYP450s) is a critical factor that should be considered in TCM prescriptions. Physcion, the major active ingredient of Rheum spp. (Polygonaceae), possesses wide pharmacol...