Design and synthesis of some new benzoylthioureido benzenesulfonamide derivatives and their analogues as carbonic anhydrase inhibitors

• Main Authors: Khulood H. Oudah (Author), Walaa R. Mahmoud (Author), Fadi M. Awadallah (Author), Azza T. Taher (Author), Safinaz E.-S Abbas (Author), Heba Abdelrasheed Allam (Author), Daniela Vullo (Author), Claudiu T. Supuran (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present investigation reports the design and synthesis of three series of benzoylthioureido derivatives bearing either benzenesulfonamide 7a-f, benzoic acid 8a-f or ethylbenzoate 9a-f moieties. The synthesised compounds were screened for their carbonic anhydrase inhibitory activity (CAI) against...