The GLP-1 agonist, liraglutide, ameliorates inflammation through the activation of the PKA/CREB pathway in a rat model of knee osteoarthritis

• Main Authors: Qihong Que (Author), Xinghua Guo (Author), Longxin Zhan (Author), Shaodong Chen (Author), Zengli Zhang (Author), Xiaoming Ni (Author), Bin Ye (Author), Shuanglin Wan (Author)
• Format: Book
• Published: BMC, 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Inflammation is a common pathological phenomenon of osteoarthritis (OA). Accumulated evidence indicates that ameliorating or suppressing inflammation might be a promising and effective therapeutic strategy for the treatment of OA. Notably, glucagon-like peptide-1 (GLP-1)-based dr...