Synthesis of thiazolidin-4-ones and thiazinan-4-ones from 1-(2-aminoethyl)pyrrolidine as acetylcholinesterase inhibitors

• Main Authors: Adriana M. das Neves (Author), Gabriele A. Berwaldt (Author), Cinara T. Avila (Author), Taís B. Goulart (Author), Bruna C. Moreira (Author), Taís P. Ferreira (Author), Mayara S. P. Soares (Author), Nathalia S. Pedra (Author), Luiza Spohr (Author), Anita A. A. dE Souza (Author), Roselia M. Spanevello (Author), Wilson Cunico (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The present study describes the synthesis of a novel series of thiazolidin-4-one and thiazinan-4-one using 1-(2-aminoethyl)pyrrolidine as amine precursor. All compounds were synthesised by one-pot three component cyclocondensation reaction from the amine, a substituted benzaldehyde and a mercaptocar...