Dasatinib Attenuates Fibrosis in Keloids by Decreasing Senescent Cell Burden

• Main Authors: Claudia C. Darmawan (Author), Keunyoung Hur (Author), Novi Kusumaningrum (Author), Jin Ho Chung (Author), Si-Hyung Lee (Author), Je-Ho Mun (Author)
• Format: Book
• Published: Medical Journals Sweden, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Keloids are skin tumours caused by aberrant growth of dermal fibroblasts. Cellular senescence contributes to aging and various pathological conditions, including cancer, atherosclerosis, and fibrotic diseases. However, the effects of cellular senescence and senolytic drugs on keloids remain largely...