PEGylated Human Serum Albumin: Review of PEGylation, Purification and Characterization Methods

• Egile Nagusiak: Parvin Akbarzadehlaleh (Egilea), Mona Mirzaei (Egilea), Mahdiyeh Mashahdi-Keshtiban (Egilea), Karim Shamsasenjan (Egilea), Hamidreza Heydari (Egilea)
• Formatua: Liburua
• Argitaratua: Tabriz University of Medical Sciences, 2016-09-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Human serum albumin (HSA) is a non-glycosylated, negatively charged protein (Mw: about 65-kDa) that has one free cystein residue (Cys 34), and 17 disulfide bridges that these bridges have main role in its stability and longer biological life-time (15 to 19 days). As HSA is a multifunctional protein,...