Micelles of Progesterone for Topical Eye Administration: Interspecies and Intertissues Differences in Ex Vivo Ocular Permeability

• Main Authors: Adrián M. Alambiaga-Caravaca (Author), María Aracely Calatayud-Pascual (Author), Vicent Rodilla (Author), Angel Concheiro (Author), Alicia López-Castellano (Author), Carmen Alvarez-Lorenzo (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Progesterone (PG) may provide protection to the retina during retinitis pigmentosa, but its topical ocular supply is hampered by PG poor aqueous solubility and low ocular bioavailability. The development of efficient topical ocular forms must face up to two relevant challenges: Protective barriers o...