The randomized, single‐ and multiple‐ ascending dose studies of the safety, tolerability, pharmacokinetics of CSPCHA115 in healthy Chinese subjects

• Egile Nagusiak: Shan Jing (Egilea), Wenfang Liu (Egilea), Kexu Yang (Egilea), Yang Lin (Egilea), Xuekun Yao (Egilea), Guilan Sun (Egilea)
• Formatua: Liburua
• Argitaratua: Wiley, 2023-03-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Abstract CSPCHA115 is a highly selective and potent antagonist of chemoattractant receptor‐homologous molecule expressed on TH2 cells (CRTH2). This study aimed to evaluate the pharmacokinetics (PKs), safety, and tolerability of single and multiple ascending doses of CSPCHA115 in Chinese healthy subj...