A mutated recombinant subunit vaccine protects mice and guinea pigs against botulinum type A intoxication

• Main Authors: Chi Ho Yu (Author), Dong Hyun Song (Author), Jun Young Choi (Author), Hae Eun Joe (Author), Woo Hyeon Jeong (Author), Gyeung Haeng Hur (Author), Young Kee Shin (Author), Seong Tae Jeong (Author)
• Format: Bog
• Udgivet: Taylor & Francis Group, 2018-02-01T00:00:00Z.
• Fag: article
• Online adgang: Connect to this object online.

Botulinum neurotoxins (BoNTs) are the most potent toxins to mammals. A toxoid vaccine was previously used for prevention of botulinum intoxication; however, this vaccine is no longer available. Currently, no approved botulinum vaccines are available from the Food and Drug Administration (FDA). Recen...