Neuroprotective effect of phospholipase A2 from Malaysian Naja sumatrana venom against H2O2-induced cell damage and apoptosis

• Main Authors: Nur Atiqah Haizum Abdullah (Author), Nur Qisya Afifah Veronica Sainik (Author), Ezalia Esa (Author), Nur Afrina Muhamad Hendri (Author), Muhamad Rusdi Ahmad Rusmili (Author), Wayne C. Hodgson (Author), Mohd Farooq Shaikh (Author), Iekhsan Othman (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxidative stress is one of the factors involved in the pathogenesis of several neurodegenerative diseases. It has been reported that a secretory phospholipase A2 known as A2-EPTX-NSm1a has lower cytotoxicity in neuronal cells compared to its crude Naja sumatrana venom. In this study, A2-EPTX-NSm1a w...