T-type Ca2+ channel enhancer SAK3 administration improves the BPSD-like behaviors in AppNL−G-F/NL−G-F knock-in mice

• Main Authors: Tomohide Degawa (Author), Ichiro Kawahata (Author), Hisanao Izumi (Author), Yasuharu Shinoda (Author), Kohji Fukunaga (Author)
• Format: Book
• Published: Elsevier, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alzheimer's disease (AD) accounts for the majority of dementia among the elderly. In addition to cognitive impairment, behavioral and psychological symptoms (BPSD) such as depression tendency and increased aggression impose a great burden on the patient. However, there is still no rational ther...