Preformulation Studies of Novel Menthol Prodrugs with Antiparasitic Activity: Chemical Stability, In Silico, and In Vitro Permeability Assays

• Main Authors: Camila M. Clemente (Author), Renée Onnainty (Author), Nadina Usseglio (Author), Gladys E. Granero (Author), Soledad Ravetti (Author)
• Formato: Libro
• Publicado: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Acceso en liña: Connect to this object online.

Based on the demonstrated and reported trypanocidal, leishmanicidal, and antiplasmodial activities of two menthol prodrugs, it was decided to proceed with preformulation studies, which are of key relevance in the drug discovery process. The aim of this study is to examine the stability and permeabil...